18 research outputs found
New insights into the genetic etiology of Alzheimer's disease and related dementias
- Author
- Aaltonen L.
- Aaltonen V.
- Aarsland Dag
- Aavikko M.
- Abalos M.S.
- Abdelnour Carla
- Abner E.
- Abraham R.
- Adams H.
- Adams P.M.
- Adarmes-Gómez A.
- Adarmes-Gómez A.D.
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Ahmad S.
- Akinyemi R.O.
- Al-Chalabi A.
- Alarcón-Martín Emilio
- Albert M.S.
- Albin R.L.
- Alcolea Daniel
- Alegret Montserrat
- Ali M.
- Allen M.
- Allende I.R.
- Alonso M.D.
- Alonso M.D.
- Alvarez I.
- Alvarez L.
- Amer-Ferrer G.
- Amin N.
- Amouyel Philippe
- Anastasiou A.
- Anastasiou C.
- Andrade V.
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- Apostolova L.G.
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- Bastiani P.
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- Belezhanska D.
- Bellenguez Céline
- Below J.E.
- Below J.E.
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- Universitat Autònoma de Barcelona
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Get PDFCharacterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
A New Spanish Grammar, Or the Elements of the Spanish Language ...
- Publication venue
- J. Nourse
- Publication date
- 01/01/1777
- Field of study
Get PDFGenetic data from polymorphic microsatellite loci were employed to estimate paternity and maternity in a local population of nine-banded armadillos (Dasypus novemcinctus) in northern Florida. The parentage assessments took advantage of maximum likelihood procedures developed expressly for situations when individuals of neither gender can be excluded a priori as candidate parents. The molecular data for 290 individuals, interpreted alone and in conjunction with detailed biological and spatial information for the population, demonstrate high exclusion probabilities and reasonably strong likelihoods of genetic parentage assignment in many cases; low mean probabilities of successful reproductive contribution to the local population by individual armadillo adults in a given year; and statistically significant microspatial associations of parents and their offspring. Results suggest that molecular assays of highly polymorphic genetic systems can add considerable power to assessments of biological parentage in natural populations even when neither parent is otherwise known
Understanding Latina and Latino College Choice
- Author
- Astin A.W.
- Baker T.L.
- Bowen W.G.
- Bradburn E.
- Ceja M.
- Cerna O.S.
- Choy S.P.
- Coleman J.S.
- Grodsky E.
- Gándara P.
- Gándara P.
- Hossler D.
- Johnson H.P.
- McDonough P.
- McDonough P.
- McDonough P.
- McDonough P.
- Nuñez A.-M.
- Pascarella E.
- Patricia A. Pérez
- Patricia M. McDonough
- Paulsen M.B.
- Pérez L.X.
- Pérez P.A.
- Swail W.S.
- Swail W.S.
- Talavera-Bustillos V.H.
- Talavera-Bustillos V.H.
- Tinto V.
- Tornatzky L.
- U.S. Census.
- U.S. Census.
- U.S. Department of Education.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
No full textACCEPTABILITY OF FROZEN DESSERTS MADE WITH NEUTRALIZED, HYDROLYZED, FLUID COTTAGE CHEESE WHEY
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
No full textPILOT SCALE ULTRAFILTRATION OF CLARIFIED ALFALFA JUICE
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- AOAC
- Bickoff E.M.
- Byers M.
- Chayen I.H.
- Cohen M.
- Dejmek P.
- Devadas R.P.
- Eakin E.E.
- Forbes F.
- Hartman G.H.
- Henderson L.W.
- Henry K.M.
- Hermansson A.M.
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- Horton B.S.
- Huang K.H.
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- Knuckles B.E.
- Lawhon J.T.
- Lexander K.
- McDonough F.E.
- Michaels AS.
- Muller L.L.
- Neish A.C.
- Olatunbosun D.A.
- Peri C.
- Pierpoint W.S.
- Pierpoint W.S.
- Pirle N.W.
- Smith A.K.
- Subba Rau B.H.
- Whitney L.F.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
No full textBarriers in the Transfer Process for Hispanic and Hispanic Immigrant Students
- Author
- Bailey T.
- Bean J.P.
- Bernard H. R.
- Bobby C. Alexander
- Dallas County Community College District.
- Dan O'Brien
- Dewalt K.M.
- Dougherty K.J.
- Fry R.
- Geoffrey Grimes
- Hagedorn L.
- Handwerker W.P.
- Johnson A.
- Johnson J.C.
- Jun A.
- Laura Gonzalez
- LeCompte M.D.
- Martin S.A.
- McDonough P.M.
- Perez P.
- Salinas A.
- Schensul S.L.
- Swail W.S.
- Tornatzky L.G.
- U.S. Census Bureau.
- U.S. Census Bureau.
- Victor Garcia
- Weller S.C.
- Wellman J.V.
- Wilds D.
- Woodlief L.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
No full textGender as social control: A qualitative study of incarcerated youths and their siblings in greater Sacramento
- Author
- Aubert V.
- Bainbridge W.S.
- Block J.H.
- Campbell A.
- Carter D.B.
- Connell R.W.
- Eagly A.H.
- Empey L.T.
- Fagot B.I.
- Figueira-McDonough J.
- Garofalo J.
- Gibbs J.T.
- Giddens A.
- Giddens A.
- Gottfredson M.R.
- Gottfredson M.R.
- Grasmick H.G.
- Hagan J.
- Hagan J.
- Hill G.D.
- hooks b.
- Jacklin C.N.
- Jean Bottcher
- Lester D.
- Lips H.M.
- McCord J.
- Messerschmidt J.W.
- Modell J.
- Norland S.
- Renzetti C.M.
- Rubin L.B.
- Schneider D.M.
- Seydlitz R.
- Simon R.J.
- Staples R.
- Staples R.
- Steffensmeier D.J.
- Steffensmeier D.J.
- Steffensmeier D.J.
- Stockard J.
- Thorne B.
- Veevers J.E.
- Wells L.E.
- Zinn M.B.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
No full textSituation Invisibility and Attribution in Distributed Collaborations
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- Adams J.
- Aiken L.
- Alge B.J.
- Alge B.J.
- Allport G.W.
- Baron R.M.
- Bellotti V.
- Block R.A.
- Brawley L.
- Catherine Durnell Cramton
- Corn R.I.
- Craig T.Y.
- Cramton C.D.
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- Gibson C.B.
- Gilbert D.T.
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- Gilbert D.T.
- Handy C.
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- Jeanne M. Wilson
- Jonas E.
- Jones E.
- Kanawattanachai P.
- Kara L. Orvis
- Kiesler S.
- Kiesler S.
- Lea M.
- LePine J.A.
- Lupfer M.C.
- Majchrzak A.
- McDonough D.W.
- Ross L.
- Ross L.
- Short J.
- Shrout P.E.
- Silver W.S.
- Solomon C.M.
- Sproull L.
- Stajkovic A.D.
- Tidwell L.C.
- Turner J.
- Walther J.B.
- Walther J.B.
- Wang Z.
- Weaver J.L.
- Weiner B.
- Weisband S.
- Wilson J.M.
- Winter L.
- Winter L.
- Zaccaro S.J.
- Zaccaro S.J.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
No full textToward a Wittgensteinian Social Psychology of Human Development
- Author
- Astington J.W.
- Baker G.P.
- Budd M.
- Burge T.
- Chihara C.
- Costell A.
- Coulter J.
- Coulter J.
- Dewey J.
- Easton S.M.
- Finch H.L.
- Fodor J.
- Fodor J.
- Frye D.
- Gilbert M.
- Gilbert M.
- Gustafson D.F.
- Habermas J.
- Hacking I.
- Hintikka J.
- Hunter J.F.M.
- Hyman J.
- John T. Jost
- Jost J.T.
- Kenny A.
- Lear J.
- Livesley W.J.
- Louch A.R.
- Malcolm N.
- McDonough R.
- Mead G.H.
- Mead G.H.
- Newman F.
- Perner J.
- Quine W.V.O.
- Rholes W.S.
- Rorty R.
- Rubinstein D.
- Rubinstein D.
- Seabright P.
- Shekelton J.F.
- Sherif M.
- Shotter J.
- Suter R.
- Tiles J.E.
- Trigg R.
- Turner J.C.
- Vygotsky L.S.
- Wellman H.U.
- Wertsch J.V.
- Whiten A.
- Winch P.
- Wittgenstein L.
- Wittgenstein L.
- Wittgenstein L.
- Wittgenstein L.
- Wittgenstein L.
- Wittgenstein L.
- Wittgenstein L.
- Zabeeh F.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
No full textOn the crystallization conditions of the Neoproterozoic, high-K calc-alkaline, Bragança Paulista-type magmatism, southern Brasília Orogen, SE Brazil
- Author
- Abdel-Rahman A.F.M.
- Anderson J.L.
- Anderson J.L.
- Artur A.C.
- Artur A.C.
- Balsley J.R.
- Blundy J.D.
- Boehnke P.
- Broska I.
- Campos Neto M. da C.
- Campos Neto M. da C.
- Campos Neto M. da C.
- Campos Neto M. da C.
- Campos Neto M. da C.
- Campos Neto M.D.C.
- Carmichael I.S.E.
- Clarke D.B.
- Czamanske G.K.
- Deer W.
- Deer W.A.
- Del Lama E.A.
- Ebert H.D.
- Erdmann S.
- Frost B.R.
- Frost B.R.
- Frost B.R.
- Fuhrman M.L.
- Galembeck T.M.B.
- Galembeck T.M.B.
- Geuna S.E.
- Ghiorso M.S.
- Ghiorso M.S.
- Ghiorso M.S.
- Gualda G.A.R.
- Gualda G.A.R.
- Gualda G.A.R.
- Guidotti C.V.
- Hackspacher P.C.
- Haddad R.C.
- Haddad R.C.
- Hammarstrom J.M.
- Harlov D.E.
- Hawthorne F.C.
- Henry D.J.
- Holland T.
- Icenhower J.P.
- Ishihara S.
- Janasi V. de A.
- Janasi V. de A.
- Janasi V.D.A.
- Korneliussen A.
- Le Maitre R.W.
- Leake B.E.
- Martins L.
- Martins L.
- Mason R.A.
- McDonough W.F.
- McEnroe S.A.
- McGuire A.
- Mehdilo A.
- Miller C.F.
- Molina J.F.
- Mori P.E.
- Munoz J.L.
- Munoz J.L.
- Mutch E.J.F.
- Nachit H.
- Navarro M.S.
- Noyes H.J.
- Pascholati E.M.
- Pitcher W.S.
- Richards J.P.
- Ridolfi F.
- Ridolfi F.
- Rocha B.C.
- Rollinson H.R.
- Salazar Mora C.A.
- Salazar-Naranjo A.F.
- Sauerzapf U.
- Schmidt M.W.
- Teiber H.
- Trouw R.A.J.
- Töpfner C.
- Vinagre R.
- Vlach S.R.F.
- Vlach S.R.F.
- Vlach S.R.F.
- Vlach S.R.F.
- Vyhnal C.R.
- Watson E.B.
- Watson E.B.
- Wernick E.
- Wones D.R.
- Wones D.R.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
No full text
